Chadwick Boseman, who played Black American icons Jackie Robinson and James Brown with searing intensity before inspiring audiences worldwide as the regal Black Panther in Marvel’s blockbuster movie franchise, died Friday of cancer. He was 43.

Boseman died at his home in the Los Angeles area with his wife and family by his side, his publicist Nicki Fioravante told The Associated Press.

Boseman was diagnosed with colon cancer four years ago, his family said in a statement.

“A true fighter, Chadwick persevered through it all, and brought you many of the films you have come to love so much,” his family said. “From Marshall to Da 5 Bloods, August Wilson’s Ma Rainey’s Black Bottom and several more – all were filmed during and between countless surgeries and chemotherapy. It was the honor of his career to bring King T’Challa to life in Black Panther.”

Read more in AP.